Hotels in Seneca, SC

For camping and shelter reservations please visit www.reserveamerica.com

Lakeside Lodge Clemson is a 189-unit condo-hotel and luxury lakefront resort located within minutes

Keowee Marina is your ultimate destination for all things boating near Lake Keowee! We are a full-service public marina located on Lake Keowee in Seneca, SC. We offer Lake Keowee...

We are the Award Winning Hotel you're looking for! Conveniently located 1.5miles from Clemson Memorial Stadium! 2025 Recipient of Tru by Hilton's Award of Excellence! Call Today to...

Find great customer service and amenities while staying at this full service Seneca, South Carolina hotel. This Seneca hotel also offers convenient access to many local attractions...

Welcome to Keowee Marina’s newest vacation rentals, Keowee Luxury Cottages located on Lake Keowee! Our stunning A-frame cottages feature 3 spacious bedrooms and 3 modern bathrooms...

RV Park with full hook-up near Clemson, SC. Go Tigers!

boat, trailer, and classic car rentals. check out our page & reach out to us for booking options!

Experience the ultimate getaway on Lake Keowee at Palmetto Paradise Houseboat Rental, located at Keowee Marina. Book your stay today at https://palmettoparadisehouseboat.com

Just home away!!!

New Lake Front home rental on Lake Keowee, 13.9 miles from Clemson University

Your go-to property management company located in Seneca SC! Let us host your stay!

We specialize in premium watercraft rentals and luxury lake experiences, including: 🚤 Jet Ski Rentals 🛥️ Boat Rentals ⚓ Yacht Charters 🌅 Sunset Cruises 🏄 Lake Adventures

Welcome to the Hampton Inn & Suites Seneca-Clemson Area, a warm and welcoming hotel just a short distance from Lake Keowee and downtown Seneca, SC. Enjoy easy access to local resta...

HydroShare is the Premier Watercraft Rental Community! To list, you simply need to provide details about your watercraft and then sit back and wait for rental requests to come in. ...

Stay Southerly offers cozy, classy getaways in Upstate SC. From Lake Jocassee cabins to the luxury of Falling Water Resort and Keowee Lake Haven, experience Southern charm and unfo...

Sunset Cove is located on Lake Keowee, SC

Our family's unique vacation rental home on Lake Keowee. Featuring post and beam construction and sitting on nearly 18 acres of wooded, private land.

Household, RV & Boat StorageOpen to service your needs 24 hours a day 7 days a week

Seneca, SC - 4 Bedroom with Stunning Lake Views from Oversized Decks on a Tranquil Setting! Amazing lakefront retreat ready to host your entire family! This 4 bedroom house is furn...

Lake Home for weekly rental 7 bedroom, 5 1/2 bath with lovely outdoor space including firepit and d

This is a family home dedicated to the memory of Gloria Parker Jenkins

Eades Campground can be enjoyed annually. The park is set up so you can lease a lot for a year or lo

With our Lake House Rentals you can plan the perfect lake vacation get away right on Lake Hartwell

Turtle Cove is a lovely luxurious lakehouse on beautiful Lake Keowee

Cozy, new lake house on Lake Keowee, SC where memories are created and shared.